This presentation examines practical approaches to implementing generative AI in healthcare environments, based on AWS's experience with healthcare organizations globally. We will discuss current implementation patterns, evaluation frameworks, and governance models that enable successful deployment of these technologies in clinical settings. Drawing from real-world examples, we will explore key considerations for model selection, deployment strategies, and performance monitoring that ensure reliable results in healthcare environments. The discussion will address common implementation challenges and their solutions, with particular focus on maintaining clinical quality and patient safety. The session includes a demonstration of an autonomous clinical agent, illustrating how healthcare organizations can expand their AI capabilities beyond foundation models. Attendees will gain practical insights for evaluating and implementing generative AI technologies while maintaining alignment with clinical standards.