In this session, we will discuss how AI and QI methods and applications can serve as a virtuous cycle, accelerating and harmonizing real-world adoption of advanced AI methods into clinical environments. We will also review lessons learned from a series of case-studies in applying AI methods to clinical QI projects. Learner Objectives: 1. Evaluate AI tools and methodologies for QI applications 2. Evaluate QI approaches to sustainable AI solutions 3. Review lessons learned in early AI/QI prototyping projects