As a physician-scientist (medical oncologist), my research program focuses on developing more effective therapies and molecular diagnostics for patients with cancer. The characterization of genetic-based alterations in model systems and bio-liquids using advanced molecular profiling and high-throughput technologies are active and significant interests.

Areas of emphasis include: drug development utilizing model systems, cancer biology, bioinformatics, advanced molecular profiling (NGS, mass spec-based proteomics), & advanced tissue microdissection (eg, LCM). As the inaugural Director of the UAMS Genomics Sequencing Facility, now provided are state-of-the-art capabilities for solid tissues (including FFPE) and bio-liquids, eg, WGS (including ultra-low-pass), panels using UMIs, scRNA-seq (10x), advanced epigenetics & bioinformatics.

Prior to medical school, I worked as an engineer for the Sperry/Unisys Corp for six years. Rising thru the ranks, I directed a group of five engineers on R&D projects involving systems level software (OS, compilers), advanced avionic software and systems integration with innovative instrumentation.